Improving Skin Lesion Detection with Transformer-Based Architectures

This article describes the methodology for adjusting and comparing eleven variants of Transformer architectures for the classification of skin lesions using images: five variants of Google’s Vision Transformer (ViT) and six variants of Microsoft’s Swin Transformer. We present the methodology used to achieve these results, which includes meticulous hyperparameter tuning and a robust data augmentation strategy to address the class imbalance problem. This approach allowed us to surpass the state of the art on the DermaMNIST dataset with respect to CNN-based models, and achieve very competitive results on the ISIC Challenge 2019 dataset with respect to Transformer-based models. In addition, we employed the CheferCAM method to provide visual explanations that identify the most influential image regions in the models’ predictions.

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Published
2026-02-01
DOI
https://doi.org/10.3390/info17020130
Primary Topic
Cutaneous Melanoma Detection and Management
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article
Field-Weighted Citation Impact
0.00

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article

Improving Skin Lesion Detection with Transformer-Based Architectures

Diego Renza, Andrés Villamarín-Olmos
Information
Cutaneous Melanoma Detection and Management
article

Improving Skin Lesion Detection with Transformer-Based Architectures

Diego Renza, Andrés Villamarín-Olmos
article en

Abstract

This article describes the methodology for adjusting and comparing eleven variants of Transformer architectures for the classification of skin lesions using images: five variants of Google’s Vision Transformer (ViT) and six variants of Microsoft’s Swin Transformer. We present the methodology used to achieve these results, which includes meticulous hyperparameter tuning and a robust data augmentation strategy to address the class imbalance problem. This approach allowed us to surpass the state of the art on the DermaMNIST dataset with respect to CNN-based models, and achieve very competitive results on the ISIC Challenge 2019 dataset with respect to Transformer-based models. In addition, we employed the CheferCAM method to provide visual explanations that identify the most influential image regions in the models’ predictions.

InformationVol. 17(2)
Military University Nueva Granada (CO)
Universidad Militar Nueva Granada
Industry, innovation and infrastructure
Openalex Percentile: Top 72%
Cutaneous Melanoma Detection and Management
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Improving Skin Lesion Detection with Transformer-Based Architectures — Diego Renza, Andrés Villamarín-Olmos · Information (2026) | TGRS Research Map | TGRS