The Combined Use of Hydroxymethylbutyrate and Branched-Chain Amino Acids to Counteract Uremic Sarcopenia

In HD patients, this FFSMP produced favorable changes in markers of muscle mass and systemic inflammation without affecting short-term physical performance. These findings support the potential clinical utility of targeted amino acid supplementation in this patient population, highlighting the need for larger, longer-term trials.

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Publication Details

Journal
Nutrients
Published
2026-02-01
DOI
https://doi.org/10.3390/nu18030483
Primary Topic
Dialysis and Renal Disease Management
Type
article
Field-Weighted Citation Impact
0.00
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article

The Combined Use of Hydroxymethylbutyrate and Branched-Chain Amino Acids to Counteract Uremic Sarcopenia

Annalisa Noce, Anna Paola Mitterhofer, Giulia Marrone, Roberto Palumbo et al.
Nutrients
Dialysis and Renal Disease Management
article

The Combined Use of Hydroxymethylbutyrate and Branched-Chain Amino Acids to Counteract Uremic Sarcopenia

Annalisa Noce, Anna Paola Mitterhofer, Giulia Marrone, Roberto Palumbo, Manuela Di Lauro, Kevin Cornali, Gabriele D’Urso, Sabri Shamsan Hassan, Sara Dominijanni, Luca Di Marco
article en

Abstract

In HD patients, this FFSMP produced favorable changes in markers of muscle mass and systemic inflammation without affecting short-term physical performance. These findings support the potential clinical utility of targeted amino acid supplementation in this patient population, highlighting the need for larger, longer-term trials.

NutrientsVol. 18(3)
University of Rome Tor Vergata (IT), University of Verona (IT), Policlinico Tor Vergata (IT), St. Eugenio Hospital (IT), Ospedale SS. Annunziata (IT)
Zero hunger
Openalex Percentile: Top 74%
Dialysis and Renal Disease Management
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