MRI-based habitat radiomics for predicting WHO/ISUP nuclear grade in clear cell renal cell carcinoma

The nomogram, which integrates intratumoral, peritumoral and habitat radiomic features derived from MRI, demonstrated excellent performance for noninvasive preoperative prediction of WHO/ISUP nuclear grade in ccRCC and holds promise as an adjunctive tool for individualized therapy planning and prognostic assessment. However, its clinical application requires further external validation.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-01-30
DOI
https://doi.org/10.3389/fonc.2026.1751579
Primary Topic
Renal cell carcinoma treatment
Type
article
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article

MRI-based habitat radiomics for predicting WHO/ISUP nuclear grade in clear cell renal cell carcinoma

Chong Liu, Naijing Shi, Cong Zhang, Xinyi Li et al.
Frontiers in Oncology
Renal cell carcinoma treatment
article

MRI-based habitat radiomics for predicting WHO/ISUP nuclear grade in clear cell renal cell carcinoma

Chong Liu, Naijing Shi, Cong Zhang, Xinyi Li, Mohan Hao
article en

Abstract

The nomogram, which integrates intratumoral, peritumoral and habitat radiomic features derived from MRI, demonstrated excellent performance for noninvasive preoperative prediction of WHO/ISUP nuclear grade in ccRCC and holds promise as an adjunctive tool for individualized therapy planning and prognostic assessment. However, its clinical application requires further external validation.

Frontiers in OncologyVol. 16
Chengde Medical University (CN), Baoding People's Hospital (CN)
Life in Land
Openalex Percentile: Top 72%
Renal cell carcinoma treatment
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