Makorin Ring Finger Protein 1 Inhibits Cell Proliferation in Renal Angiomyolipoma via the ERK/MAPK Signaling Pathway

This study demonstrates that MKRN1 mediates AML cell proliferation by regulating the ERK/MAPK signaling pathway. These findings suggest that MKRN1 plays a crucial role in AML progression and may serve as a potential diagnostic and therapeutic biomarker for AML.

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Publication Details

Journal
Kidney Diseases
Published
2026-01-30
DOI
https://doi.org/10.1159/000550747
Primary Topic
Tuberous Sclerosis Complex Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Makorin Ring Finger Protein 1 Inhibits Cell Proliferation in Renal Angiomyolipoma via the ERK/MAPK Signaling Pathway

TZU-HSUAN CHANG, Cheng-Keng Chuang, Ying-Hsu Chang, Tzu-Kai Wang et al.
Kidney Diseases
Tuberous Sclerosis Complex Research
article

Makorin Ring Finger Protein 1 Inhibits Cell Proliferation in Renal Angiomyolipoma via the ERK/MAPK Signaling Pathway

TZU-HSUAN CHANG, Cheng-Keng Chuang, Ying-Hsu Chang, Tzu-Kai Wang, Chung-Yi Liu, Jacob See-Tong Pang
article en

Abstract

This study demonstrates that MKRN1 mediates AML cell proliferation by regulating the ERK/MAPK signaling pathway. These findings suggest that MKRN1 plays a crucial role in AML progression and may serve as a potential diagnostic and therapeutic biomarker for AML.

Kidney DiseasesVol. 12(1)
Chang Gung University (TW), Taipei Municipal YangMing Hospital (TW), Linkou Chang Gung Memorial Hospital (TW), Taipei City Hospital (TW)
Good health and well-being
Openalex Percentile: Top 71%
Tuberous Sclerosis Complex Research
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