Transgenerational fitness and transcriptomic responses of <scp> <i>Binodoxys communis</i> </scp> to chlorantraniliprole

This study provides the first evidence of transgenerational detrimental effects of chlorantraniliprole on B. communis and functionally validates the critical role of BcIVD under insecticide stress. Our findings highlight the need to incorporate molecular and transgenerational outputs into the evaluation of insecticide impacts, and offer valuable insights for developing conservation biological control strategies. Future research should build directly upon these findings, particularly by investigating the molecular mechanisms underlying BcIVD-mediated susceptibility, such as its specific role in detoxification and its interactions with other resistance-related genes. © 2026 Society of Chemical Industry.