Neuroendocrine tumor arising in Meckel’s diverticulum presenting with bowel obstruction

Meckel's diverticulum (MD) is a common developmental abnormality of the gastrointestinal tract that, in adults, is usually asymptomatic but can present with complications including malignancy. Although malignancy in MD is rare overall, MD is recognized a high-risk site for tumorigenesis compared to the surrounding ileum. Neuroendocrine neoplasms are the most common malignancy arising in MD and are often associated with nodal metastases, even if the primary tumor is small. We report the case of a 66-year-old male who underwent exploratory laparotomy for small bowel obstruction and was intraoperatively found to have MD causing an internal hernia. Pathologic examination of the diverticulectomy specimen revealed a well-differentiated neuroendocrine tumor, grade 1, pathologic stage pT2. The case highlights the role of resection for incidentally found and symptomatic MD due to the elevated risk of malignancy at this site.

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Publication Details

Journal
Journal of Surgical Case Reports
Published
2025-12-24
DOI
https://doi.org/10.1093/jscr/rjag025
Primary Topic
Gastrointestinal disorders and treatments
Type
article
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article

Neuroendocrine tumor arising in Meckel’s diverticulum presenting with bowel obstruction

James H. McClenathan, Jillian C. Dawley, Belinda L Sun
Journal of Surgical Case Reports
Gastrointestinal disorders and treatments
article

Neuroendocrine tumor arising in Meckel’s diverticulum presenting with bowel obstruction

James H. McClenathan, Jillian C. Dawley, Belinda L Sun
article en

Abstract

Meckel's diverticulum (MD) is a common developmental abnormality of the gastrointestinal tract that, in adults, is usually asymptomatic but can present with complications including malignancy. Although malignancy in MD is rare overall, MD is recognized a high-risk site for tumorigenesis compared to the surrounding ileum. Neuroendocrine neoplasms are the most common malignancy arising in MD and are often associated with nodal metastases, even if the primary tumor is small. We report the case of a 66-year-old male who underwent exploratory laparotomy for small bowel obstruction and was intraoperatively found to have MD causing an internal hernia. Pathologic examination of the diverticulectomy specimen revealed a well-differentiated neuroendocrine tumor, grade 1, pathologic stage pT2. The case highlights the role of resection for incidentally found and symptomatic MD due to the elevated risk of malignancy at this site.

Journal of Surgical Case ReportsVol. 2026(1)
Banner - University Medical Center Tucson (US)
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Openalex Percentile: Top 23%
Gastrointestinal disorders and treatments
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Neuroendocrine tumor arising in Meckel’s diverticulum presenting with bowel obstruction — James H. McClenathan, Jillian C. Dawley, et al. · Journal of Surgical Case Reports (2025) | TGRS Research Map | TGRS