Functional and Clinical: An Explainable Deep Learning Model for Multimodal Alzheimer's Disease Classification

Our model was highly accurate and highlighted the importance of combining fMRI and clinical data for AD classification. These findings have implications for the refinement of multimodal deep learning models; however, our small sample and need for external validation are also noted.

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Publication Details

Journal
Brain and Behavior
Published
2026-01-30
DOI
https://doi.org/10.1002/brb3.71240
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Functional and Clinical: An Explainable Deep Learning Model for Multimodal Alzheimer's Disease Classification

Ahmed Abdelrehem, Samuel L. Warren
Brain and Behavior
Dementia and Cognitive Impairment Research
article

Functional and Clinical: An Explainable Deep Learning Model for Multimodal Alzheimer's Disease Classification

Ahmed Abdelrehem, Samuel L. Warren
article en

Abstract

Our model was highly accurate and highlighted the importance of combining fMRI and clinical data for AD classification. These findings have implications for the refinement of multimodal deep learning models; however, our small sample and need for external validation are also noted.

Brain and BehaviorVol. 16(2)
Bond University (AU), University of Johannesburg (ZA)
U.S. Department of Defense, Alzheimer's Association, Bristol-Myers Squibb, Eli Lilly and Company, Pfizer, Biogen, University of Southern California, Meso Scale Diagnostics, BioClinica, Novartis Pharmaceuticals Corporation, Northern California Institute for Research and Education, Australian Government, Bond University, Eisai, Servier, H. Lundbeck A/S, IXICO, National Institutes of Health, Genentech, Canadian Institutes of Health Research
Openalex Percentile: Top 72%
Dementia and Cognitive Impairment Research
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