Exploring the Causal Links Between <i>Toxoplasma gondii</i> Infection and Risk of Brain Tumors: A Bidirectional Mendelian Randomization Analysis

Our study provides no evidence for a causal relationship between genetic liability to T. gondii seropositivity and brain tumor risk. However, reverse MR suggests that genetic liability to malignant brain tumors may be associated with increased odds of T. gondii infection.

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Publication Details

Journal
Brain and Behavior
Published
2026-01-29
DOI
https://doi.org/10.1002/brb3.71239
Primary Topic
Toxoplasma gondii Research Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Exploring the Causal Links Between Toxoplasma gondii Infection and Risk of Brain Tumors: A Bidirectional Mendelian Randomization Analysis

Gangao Wei, Y Wang, Jiaqi Zhang, Zhang Cheng et al.
Brain and Behavior
Toxoplasma gondii Research Studies
article

Exploring the Causal Links Between Toxoplasma gondii Infection and Risk of Brain Tumors: A Bidirectional Mendelian Randomization Analysis

Gangao Wei, Y Wang, Jiaqi Zhang, Zhang Cheng, Yunchao Chen, Baoshun Du, Zhenguo Cheng, Zhenwei Li, Pengqiang Shi
article en

Abstract

Our study provides no evidence for a causal relationship between genetic liability to T. gondii seropositivity and brain tumor risk. However, reverse MR suggests that genetic liability to malignant brain tumors may be associated with increased odds of T. gondii infection.

Brain and BehaviorVol. 16(2)
Xinxiang Central Hospital (CN), Xinxiang University (CN), Henan Medical University (CN)
Good health and well-being
Openalex Percentile: Top 68%
Toxoplasma gondii Research Studies
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