A new, rapid, chemiluminescence enzyme assay for the detection of heparin-induced thrombocytopenia: a comparison between functional and immune heparin-induced thrombocytopenia assays
The HISCL HIT IgG assay had 100% sensitivity and superior specificity compared with other antigen assays. Good correlation was observed between plasma and serum samples, and the time to result was ∼25% faster than the HemosIL AcuStar HIT-IgG assay.
Authors
- Steve Kitchen (ORCID: https://orcid.org/0000-0002-6826-8519)
- Annette Bowyer (ORCID: https://orcid.org/0000-0003-3425-5848)
- Irfan Patel
- Kiyoko Kohama
- Katsushi Kobayashi
- Ayano Mukaida
- Ryo Hasegawa
- Andreas Greinacher
Institutions
- Universitätsmedizin Greifswald (DE)
- Royal Hallamshire Hospital (GB)
- Sysmex (Japan) (JP)
Publication Details
- Journal
- Research and Practice in Thrombosis and Haemostasis
- Published
- 2026-01-30
- DOI
- https://doi.org/10.1016/j.rpth.2026.103373
- Primary Topic
- Heparin-Induced Thrombocytopenia and Thrombosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Sysmex Corporation