Rethinking anti-cancer drug discovery: the evolution from polypharmacy to unified drug units

Despite advances in current anti-cancer therapies, challenges such as drug resistance, toxicity, and tumor heterogeneity persist. The limitations of traditional single-target drugs and simple combination therapies are becoming increasingly apparent[1][1]. To address these issues, a novel treatment

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Publication Details

Journal
Cancer Biology and Medicine
Published
2026-01-29
DOI
https://doi.org/10.20892/j.issn.2095-3941.2025.0641
Citations
1
Primary Topic
Protein Degradation and Inhibitors
Type
article
Field-Weighted Citation Impact
22.24
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article

Rethinking anti-cancer drug discovery: the evolution from polypharmacy to unified drug units

Jun He, Xinbing Sui
1 citations
Cancer Biology and Medicine
Protein Degradation and Inhibitors
22.24
article

Rethinking anti-cancer drug discovery: the evolution from polypharmacy to unified drug units

Jun He, Xinbing Sui
article en
1 citations

Abstract

Despite advances in current anti-cancer therapies, challenges such as drug resistance, toxicity, and tumor heterogeneity persist. The limitations of traditional single-target drugs and simple combination therapies are becoming increasingly apparent[1][1]. To address these issues, a novel treatment

Cancer Biology and MedicineVol. 23(1)
Hangzhou Normal University (CN), Affiliated Hospital of Hangzhou Normal University (CN)
Good health and well-being
Openalex Percentile: Top 2%
Protein Degradation and Inhibitors
22.24
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Rethinking anti-cancer drug discovery: the evolution from polypharmacy to unified drug units — Jun He, Xinbing Sui · Cancer Biology and Medicine (2026) | TGRS Research Map | TGRS