RAD51 promotes osteogenic differentiation and inhibits DNA damage in osteoporosis though regulating cGAS-STING signaling pathway

RAD51 facilitated osteogenic differentiation and attenuated DNA damage in OP by modulating the cGAS-STING signaling pathway, offering a potential novel therapeutic target for OP treatment.

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Publication Details

Journal
Regenerative Therapy
Published
2026-01-30
DOI
https://doi.org/10.1016/j.reth.2026.101070
Primary Topic
interferon and immune responses
Type
article
Field-Weighted Citation Impact
0.00
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article

RAD51 promotes osteogenic differentiation and inhibits DNA damage in osteoporosis though regulating cGAS-STING signaling pathway

Xinyu Wu, Liuzhong Zhou, Peili He, Yutong Jiang et al.
Regenerative Therapy
interferon and immune responses
article

RAD51 promotes osteogenic differentiation and inhibits DNA damage in osteoporosis though regulating cGAS-STING signaling pathway

Xinyu Wu, Liuzhong Zhou, Peili He, Yutong Jiang, Zhiqiang Chen, Gu Jieruo, Mingcan Yang, M. Qiu
article en

Abstract

RAD51 facilitated osteogenic differentiation and attenuated DNA damage in OP by modulating the cGAS-STING signaling pathway, offering a potential novel therapeutic target for OP treatment.

Regenerative TherapyVol. 31
Sun Yat-sen University (CN), Third Affiliated Hospital of Sun Yat-sen University (CN)
Good health and well-being
Openalex Percentile: Top 72%
interferon and immune responses
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