Correlation between quadriceps activation and proprioception in patients with knee osteoarthritis

This study indicated that during stair climb, KOA patients display a unique pattern of elevated RMS of the VM. Notable relationships were identified between the absolute error angles of JPR and sEMG parameters of VM. The pronounced positive correlations in muscle activation patterns between walking and stair upward and downward activities indicate a fixed, task-invariant neuromuscular approach in KOA patients, possibly resulting from compromised sensorimotor integration due to proprioceptive impairments. These findings offer new insights into the pathogenesis of KOA from a neuromuscular-sensory viewpoint, emphasizing the need for future rehabilitation therapies to concurrently target proprioceptive accuracy and the enhancement of muscle activation patterns.

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Publication Details

Journal
Frontiers in Bioengineering and Biotechnology
Published
2026-01-30
DOI
https://doi.org/10.3389/fbioe.2025.1735163
Primary Topic
Muscle activation and electromyography studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Correlation between quadriceps activation and proprioception in patients with knee osteoarthritis

Zhilin Ge, Yongjin Li, Dingkun Lin, Yu Hou et al.
Frontiers in Bioengineering and Biotechnology
Muscle activation and electromyography studies
article

Correlation between quadriceps activation and proprioception in patients with knee osteoarthritis

Zhilin Ge, Yongjin Li, Dingkun Lin, Yu Hou, Zibo Gao, Meiping Yang, Xiaolong Zeng
article en

Abstract

This study indicated that during stair climb, KOA patients display a unique pattern of elevated RMS of the VM. Notable relationships were identified between the absolute error angles of JPR and sEMG parameters of VM. The pronounced positive correlations in muscle activation patterns between walking and stair upward and downward activities indicate a fixed, task-invariant neuromuscular approach in KOA patients, possibly resulting from compromised sensorimotor integration due to proprioceptive impairments. These findings offer new insights into the pathogenesis of KOA from a neuromuscular-sensory viewpoint, emphasizing the need for future rehabilitation therapies to concurrently target proprioceptive accuracy and the enhancement of muscle activation patterns.

Frontiers in Bioengineering and BiotechnologyVol. 13
Guangzhou University of Chinese Medicine (CN), Ji Hua Laboratory (CN), Key Laboratory of Guangdong Province (CN), Guangdong Provincial Hospital of Traditional Chinese Medicine (CN)
Guangdong Provincial Hospital of Traditional Chinese Medicine, China Postdoctoral Science Foundation
Gender equality
Openalex Percentile: Top 72%
Muscle activation and electromyography studies
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Correlation between quadriceps activation and proprioception in patients with knee osteoarthritis — Zhilin Ge, Yongjin Li, et al. · Frontiers in Bioengineering and Biotechnology (2026) | TGRS Research Map | TGRS