Peroxiredoxin 1 mediates bleomycin-induced acute lung injury in mice via macrophage NOD1/NF-κB axis
These findings identify Prdx1 as a potential therapeutic target for BLM-induced ALI, offering a strategy to mitigate its pulmonary toxicity and facilitate the broader clinical application of BLM.
Authors
- Lijun Zou
- Qingxiang Liu
- Mao Jiang (ORCID: https://orcid.org/0000-0002-0621-1349)
- Yijun He (ORCID: https://orcid.org/0000-0003-1152-2907)
- Jie Meng
- Pan Yu
- Tingting Yao
- Xiaoyun Cheng
- Lingzhi Long
- Yan Zhang
- Xiangyu Zhang
- Guoliang Jiang
Institutions
- Central South University (CN)
- Yueyang Second People's Hospital (CN)
- Third Xiangya Hospital (CN)
Publication Details
- Journal
- Respiratory Research
- Published
- 2026-01-30
- DOI
- https://doi.org/10.1186/s12931-026-03533-5
- Primary Topic
- Redox biology and oxidative stress
- Type
- article
- Field-Weighted Citation Impact
- 0.00