Non‐Melanoma Skin Cancer in Transplant Recipients: A Single‐Centre Retrospective Cohort Study on the Role of Transplant Type, Immunosuppressive Exposure, and Tumor Subtypes

In this long-term cohort, NMSC risk increased with age at first transplant, whereas transplant organ and ever-use of major immunosuppressive agents were not independently associated in adjusted models. Over an extended follow-up, NMSC accumulated steadily, with crude incidence rates around 1.88-2.68 cases per 100 person-years across immunosuppressive classes and agents, underscoring the cumulative nature of skin cancer risk under chronic immunosuppression. Our results reinforce the need for sustained, long-term dermatologic surveillance, particularly in older patients undergoing transplantation.

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Publication Details

Journal
Clinical Transplantation
Published
2026-01-30
DOI
https://doi.org/10.1111/ctr.70451
Primary Topic
Nonmelanoma Skin Cancer Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Non‐Melanoma Skin Cancer in Transplant Recipients: A Single‐Centre Retrospective Cohort Study on the Role of Transplant Type, Immunosuppressive Exposure, and Tumor Subtypes

Corrado Zengarini, Bianca Maria Piraccini, Gioia Sorbi, M. La Plaça et al.
Clinical Transplantation
Nonmelanoma Skin Cancer Studies
article

Non‐Melanoma Skin Cancer in Transplant Recipients: A Single‐Centre Retrospective Cohort Study on the Role of Transplant Type, Immunosuppressive Exposure, and Tumor Subtypes

Corrado Zengarini, Bianca Maria Piraccini, Gioia Sorbi, M. La Plaça, Alba GUGLIELMO, Marco Pignatti, Vittoria Tagnin, Alessandro Pileri
article en

Abstract

In this long-term cohort, NMSC risk increased with age at first transplant, whereas transplant organ and ever-use of major immunosuppressive agents were not independently associated in adjusted models. Over an extended follow-up, NMSC accumulated steadily, with crude incidence rates around 1.88-2.68 cases per 100 person-years across immunosuppressive classes and agents, underscoring the cumulative nature of skin cancer risk under chronic immunosuppression. Our results reinforce the need for sustained, long-term dermatologic surveillance, particularly in older patients undergoing transplantation.

Clinical TransplantationVol. 40(2)
University of Ferrara (IT), Azienda USL di Bologna (IT), University of Bologna (IT)
Università di Bologna
Good health and well-being
Openalex Percentile: Top 70%
Nonmelanoma Skin Cancer Studies
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