Predicting off-track development in infants aged 0–6 months in low-resource settings using machine learning

Early intervention programs are proven to enhance optimal childhood development, yet the vital step of early identification of developmental delays is often overlooked. While machine learning is increasingly used to predict or identify health outcomes, its application in identifying developmental outcomes, particularly in low-resource settings, remains limited. This study contributes to the literature by applying machine learning to identify infants who are developmentally off-track and highlights key predictors. Limited psychosocial stimulation and increasing infant age were the strongest predictors, alongside low socioeconomic status, maternal mental health challenges, limited healthcare access, and nutritional and biological risks.

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Publication Details

Journal
Pediatric Research
Published
2026-01-30
DOI
https://doi.org/10.1038/s41390-026-04761-7
Primary Topic
Infant Development and Preterm Care
Type
article
Field-Weighted Citation Impact
0.00

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article

Predicting off-track development in infants aged 0–6 months in low-resource settings using machine learning

Rachel A Odhiambo, Anthony Kiratu Ngugi, Fred J. Benson, Felix Agoi et al.
Pediatric Research
Infant Development and Preterm Care
article

Predicting off-track development in infants aged 0–6 months in low-resource settings using machine learning

Rachel A Odhiambo, Anthony Kiratu Ngugi, Fred J. Benson, Felix Agoi, Terry A. Vik, Akbar K. Waljee, Ji Zhu, Amina Abubakar, Willie Brink
article en

Abstract

Early intervention programs are proven to enhance optimal childhood development, yet the vital step of early identification of developmental delays is often overlooked. While machine learning is increasingly used to predict or identify health outcomes, its application in identifying developmental outcomes, particularly in low-resource settings, remains limited. This study contributes to the literature by applying machine learning to identify infants who are developmentally off-track and highlights key predictors. Limited psychosocial stimulation and increasing infant age were the strongest predictors, alongside low socioeconomic status, maternal mental health challenges, limited healthcare access, and nutritional and biological risks.

Pediatric Research
Stellenbosch University (ZA), University of Michigan (US), Kenya Medical Research Institute (KE), University of Oxford (GB), Aga Khan University Nairobi (KE), Center for Global Health (US), United States International University Africa (KE)
University of Michigan, National Institutes of Health, National Institute of Mental Health, Fogarty International Center, National Institute of Biomedical Imaging and Bioengineering
Openalex Percentile: Top 71%
Infant Development and Preterm Care
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