Cell division cycle 42 binding protein beta as a plasma-based biomarker for cerebral cavernous malformations
The authors present data supporting the measurement of CDC42BPB plasma level as a putative biomarker for CCMs. These findings have implications relevant to improving diagnosis, follow-up, and molecular pathophysiological analysis.
Authors
- Tyra Martinez
- Karthik Ashok
- Aram Ghalali
- Edward R. Smith (ORCID: https://orcid.org/0000-0002-7434-5912)
- Alexander M. Tucker
- Adrien Lupieri (ORCID: https://orcid.org/0000-0002-9245-0169)
- Gregory G. Heuer (ORCID: https://orcid.org/0000-0002-1989-0141)
- Julie Sesen
- Shih-Shan Lang
- Yousef Hattar
Institutions
- Brigham and Women's Hospital (US)
- Boston Children's Hospital (US)
- Children's Hospital of Philadelphia (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Journal of Neurosurgery Pediatrics
- Published
- 2026-01-30
- DOI
- https://doi.org/10.3171/2025.9.peds25375
- Primary Topic
- Vascular Malformations Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00