Oxytocin and Vasopressin Cross Talk Within the Brain Increases Blood Pressure
Collectively, our results reveal that firing of PVN<sup>OXT</sup> promotes paracrine release of OXT, which via activation of V1aR(s) expressed on vasopressin-synthesizing neurons of the paraventricular nucleus, drives vasopressin secretion that elevates SBP.
Authors
- Matthew K. Kirchner (ORCID: https://orcid.org/0000-0001-6960-7685)
- Jieqiang Zhou
- Annette D. de Kloet (ORCID: https://orcid.org/0000-0002-7213-6957)
- Eric G. Krause (ORCID: https://orcid.org/0000-0002-2718-3113)
- Yalun Tan (ORCID: https://orcid.org/0000-0003-0786-7865)
- Dominique N. Johnson (ORCID: https://orcid.org/0000-0002-8421-043X)
- Caitlin Baumer-Harrison (ORCID: https://orcid.org/0000-0002-6287-5887)
- Yinzhi Lang (ORCID: https://orcid.org/0000-0002-6857-4516)
- Khalid Elsaafien (ORCID: https://orcid.org/0000-0001-9581-918X)
- Carly J. Vincent
- Javier E. Stern
- Yongzhen Zhang
- Karen A. Scott
Institutions
- American Association of Colleges of Pharmacy (US)
- University of Florida (US)
- Norwegian Womens Public Health Association (NO)
- University of Pennsylvania (US)
- Louisiana State University Health Sciences Center Shreveport (US)
- Texas A&M University (US)
- Florida College (US)
Publication Details
- Journal
- Circulation Research
- Published
- 2026-01-30
- DOI
- https://doi.org/10.1161/circresaha.125.327322
- Primary Topic
- Neuroendocrine regulation and behavior
- Type
- article
- Field-Weighted Citation Impact
- 0.00