Revealing interactions between microbes, metabolites, and dietary compounds using genome-scale analysis
Our results quantitatively reveal large-scale variation and redundancy in gut microbial metabolism and identify dietary compounds linked to only a few microbial species. These findings improve understanding of microbe-metabolite interactions and provide a foundation for the rational design of microbiome-based interventions for healthy benefits. Video Abstract.
Authors
- Yan Qin Tan (ORCID: https://orcid.org/0000-0002-7529-9807)
- Giulia Menichetti (ORCID: https://orcid.org/0000-0001-5201-6774)
- Tong Wang (ORCID: https://orcid.org/0009-0002-6566-6893)
- Scott T. Weiss
- Benjamin M. Gyori
Institutions
- Brigham and Women's Hospital (US)
- Northeastern University (US)
- Harvard University (US)
- Purdue University West Lafayette (US)
- Dana-Farber/Harvard Cancer Center (US)
Publication Details
- Journal
- Microbiome
- Published
- 2026-01-30
- DOI
- https://doi.org/10.1186/s40168-025-02312-6
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00