Dose-response meta-analysis of plasma TMAO and stroke: validated linear risk threshold at 3.0 μmol/L

TMAO exhibits a linear, dose-dependent association with stroke risk, with ≥ 3.0 μmol/L serving as a critical threshold for clinical intervention.

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Publication Details

Journal
Frontiers in Neurology
Published
2026-01-30
DOI
https://doi.org/10.3389/fneur.2026.1749522
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.00
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article

Dose-response meta-analysis of plasma TMAO and stroke: validated linear risk threshold at 3.0 μmol/L

Jiakai Zhang, Lefang Liu, Ruizhi Luan, Tao Yu
Frontiers in Neurology
Gut microbiota and health
article

Dose-response meta-analysis of plasma TMAO and stroke: validated linear risk threshold at 3.0 μmol/L

Jiakai Zhang, Lefang Liu, Ruizhi Luan, Tao Yu
article en

Abstract

TMAO exhibits a linear, dose-dependent association with stroke risk, with ≥ 3.0 μmol/L serving as a critical threshold for clinical intervention.

Frontiers in NeurologyVol. 17
Maternal and Child Health Care Hospital of Bao'an (CN)
Good health and well-being
Openalex Percentile: Top 72%
Gut microbiota and health
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