Prognostic Value and Potential Mechanism of CD8+ T Subsets Phenotype in ICU Patients with Sepsis
CD8+ T-cell subset phenotypes serve as important prognostic indicators in sepsis, with IL-12Rβ1 potentially being a key molecule affecting CD8+ T-cell function, providing a new potential target for sepsis monitoring and immunotherapy.
Authors
- Yawen Xie (ORCID: https://orcid.org/0000-0002-3621-2529)
- Guoyu Zhao
- Xianli Lei
- Hao Wang (ORCID: https://orcid.org/0000-0001-6881-9977)
- Na Cui
- Jiahui Zhang
- Yun Long
Institutions
- Beth Israel Deaconess Medical Center (US)
- Harvard University (US)
- Capital Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking University (CN)
- Beijing Chao-Yang Hospital, Capital Medical University (CN)
- Peking Union Medical College Hospital (CN)
- Beijing Jishuitan Hospital (CN)
Publication Details
- Journal
- Shock
- Published
- 2025-10-21
- DOI
- https://doi.org/10.1097/shk.0000000000002730
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00