Meningeal lymphatic vessel dysfunction exacerbates brain injury in CVST mice via endoplasmic reticulum and oxidative stress pathways
Dysfunction of mLVs exacerbates brain injury after CVST by promoting neuroinflammation via the ER and oxidative stress pathways. Therapeutically targeting mLVs may represent promising strategies for managing CVST-related neurological injury.
Authors
- Xianqun Wu
- Junjie Jing
- Jianbin Ying (ORCID: https://orcid.org/0009-0009-9092-7347)
- Xuanjie Chen (ORCID: https://orcid.org/0009-0009-5874-8189)
- Haitao Zhang (ORCID: https://orcid.org/0000-0002-1639-4089)
- Shousen Wang (ORCID: https://orcid.org/0000-0001-5732-7846)
- Liangfeng Wei
- Jun Li
Institutions
- Fujian Medical University (CN)
- Fujian Women and Children Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-01-30
- DOI
- https://doi.org/10.3389/fimmu.2026.1745066
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Fujian Province
- Fujian Provincial Health Commission