Identification of a neoplastic Tfh-like cellular subset in a mouse model of angioimmunoblastic T cell lymphoma

Our study identified a pathogenic Tfh-like subset essential for AITL tumor progression in a mouse model and suggests that identifying and targeting a DE Tfh-like subset in AITL patients might be an effective strategy.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-01-30
DOI
https://doi.org/10.3389/fonc.2026.1715613
Primary Topic
Vascular Tumors and Angiosarcomas
Type
article
Field-Weighted Citation Impact
0.00

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article

Identification of a neoplastic Tfh-like cellular subset in a mouse model of angioimmunoblastic T cell lymphoma

J. Lee, Nikoletta Diamantopoulos, Saba Mohammaei, Junhun Cho et al.
Frontiers in Oncology
Vascular Tumors and Angiosarcomas
article

Identification of a neoplastic Tfh-like cellular subset in a mouse model of angioimmunoblastic T cell lymphoma

J. Lee, Nikoletta Diamantopoulos, Saba Mohammaei, Junhun Cho, Woong-Kyung Suh, Lifei Hou, Antoine Bouchard, Evany Bernal Ballesteros, Eileen Remold
article en

Abstract

Our study identified a pathogenic Tfh-like subset essential for AITL tumor progression in a mouse model and suggests that identifying and targeting a DE Tfh-like subset in AITL patients might be an effective strategy.

Frontiers in OncologyVol. 16
Boston Children's Hospital (US), Samsung Medical Center (KR), Montreal Clinical Research Institute (CA), Edelweiss Connect (Switzerland) (CH), McGill University (CA), Université de Montréal (CA)
Cancer Research Society
Openalex Percentile: Top 72%
Vascular Tumors and Angiosarcomas
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