High Prevalence of Cerebrovascular Calcifications and Clinical Correlates in Indigenous Bolivian Forager‐Horticulturalists: A Population‐Based Observational Study
Despite the physically active subsistence lifestyle and the low rates of typical cardiovascular risk factors and coronary artery disease, intracranial vascular calcifications are common in these Bolivian Amerindian people, suggesting that alternative factors may contribute to intracranial arteriosclerosis and a novel dementia phenotype.
Authors
- Gregory S. Thomas
- Kenneth H. Buetow (ORCID: https://orcid.org/0000-0003-4439-0939)
- Jesus Bani Cuata
- Grant D. Schleifer (ORCID: https://orcid.org/0000-0001-7544-1706)
- Giuseppe Barisano (ORCID: https://orcid.org/0000-0001-5598-1369)
- Raúl Quispe Gutierrez
- Ellen E. Walters
- Jonathan Stieglitz (ORCID: https://orcid.org/0000-0001-5985-9643)
- Hillard S Kaplan (ORCID: https://orcid.org/0000-0002-7398-7358)
- Benjamin C. Trumble (ORCID: https://orcid.org/0000-0003-3201-0628)
- Caleb E. Finch (ORCID: https://orcid.org/0000-0002-7617-3958)
- Margaret Gatz (ORCID: https://orcid.org/0000-0002-1071-9970)
- Maria Ashna
- Daniel K. Cummings (ORCID: https://orcid.org/0000-0001-7370-3020)
- Paul L. Hooper (ORCID: https://orcid.org/0000-0002-4673-7513)
- Thomas Fischbach
- Daniel Eid Rodríguez
- Chui Hc
- Wendy J. Mack
- Meng Law
- M. Linda Sutherland
- James D. Sutherland
- Bavrina Bigjahan
- Nikhil N. Chaudhari
- Jacob E. Aronoff
- Andrei Irimia
- Michael D. Gurven
Institutions
- University of Southern California (US)
- Harvard University (US)
- University of California, Santa Barbara (US)
- University of Illinois Urbana-Champaign (US)
- Chapman University (US)
- California Southern University (US)
- Australian Regenerative Medicine Institute (AU)
- University of California System (US)
- Universidad Mayor de San Simón (BO)
- University of Illinois Chicago (US)
- Toulouse School of Economics (FR)
- MemorialCare Health System (US)
- Tech Foundation (US)
- Alfred Health (AU)
- Arizona State University (US)
- Monash University (AU)
- University of Missouri–Kansas City (US)
- Stanford University (US)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2026-01-30
- DOI
- https://doi.org/10.1161/jaha.125.043028
- Primary Topic
- Paleopathology and ancient diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00