Translational approaches to childhood inflammatory brain diseases: a review

As IBrainDs often present subacute and insidious, a high index of suspicion is warranted as often CSF and MRI findings are nonspecific and specific antibody testing, angiography, or brain biopsy are necessary to confirm the diagnosis. Here we will review the main categories of IBrainDs, clinical presentation, and discuss pathophysiologic mechanisms to support treatment choices.

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Publication Details

Journal
Expert Review of Clinical Immunology
Published
2026-01-02
DOI
https://doi.org/10.1080/1744666x.2026.2625970
Primary Topic
Bacterial Infections and Vaccines
Type
article
Field-Weighted Citation Impact
0.00
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article

Translational approaches to childhood inflammatory brain diseases: a review

Paulo Rogério Júlio, Marinka Twilt, Stephanie KA Wong, Rodrigo Marchi Silva
Expert Review of Clinical Immunology
Bacterial Infections and Vaccines
article

Translational approaches to childhood inflammatory brain diseases: a review

Paulo Rogério Júlio, Marinka Twilt, Stephanie KA Wong, Rodrigo Marchi Silva
article en

Abstract

As IBrainDs often present subacute and insidious, a high index of suspicion is warranted as often CSF and MRI findings are nonspecific and specific antibody testing, angiography, or brain biopsy are necessary to confirm the diagnosis. Here we will review the main categories of IBrainDs, clinical presentation, and discuss pathophysiologic mechanisms to support treatment choices.

Expert Review of Clinical ImmunologyVol. 22(1)
University of British Columbia (CA), University of Calgary (CA), Universidade Estadual de Campinas (UNICAMP) (BR)
Good health and well-being
Openalex Percentile: Top 71%
Bacterial Infections and Vaccines
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