Beam angle optimization for radiotherapy using LLMs via reinforcement‐learning inspired iterative refinement

This study demonstrates that general-purpose LLMs, operating without specialized model training or fine-tuning, can effectively serve as intelligent agents for automated radiotherapy TP, specifically addressing the BAO problem. This flexible and scalable framework has the potential to enhance clinical decision-making workflows in radiotherapy. Future research directions include exploring more comprehensive and clinically nuanced reward functions and extending the methodology to other components of radiotherapy TP.

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Publication Details

Journal
Medical Physics
Published
2026-01-29
DOI
https://doi.org/10.1002/mp.70258
Primary Topic
Advanced Radiotherapy Techniques
Type
article
Field-Weighted Citation Impact
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article

Beam angle optimization for radiotherapy using LLMs via reinforcement‐learning inspired iterative refinement

Alessandra Carosi, Rolando Maria D'angelillo, Sara Cammarota, Nicola Toschi et al.
Medical Physics
Advanced Radiotherapy Techniques
article

Beam angle optimization for radiotherapy using LLMs via reinforcement‐learning inspired iterative refinement

Alessandra Carosi, Rolando Maria D'angelillo, Sara Cammarota, Nicola Toschi, Matteo Ferrante
article en

Abstract

This study demonstrates that general-purpose LLMs, operating without specialized model training or fine-tuning, can effectively serve as intelligent agents for automated radiotherapy TP, specifically addressing the BAO problem. This flexible and scalable framework has the potential to enhance clinical decision-making workflows in radiotherapy. Future research directions include exploring more comprehensive and clinically nuanced reward functions and extending the methodology to other components of radiotherapy TP.

Medical PhysicsVol. 53(2)
University of Rome Tor Vergata (IT), Athinoula A. Martinos Center for Biomedical Imaging (US), Radiolabs (IT)
Openalex Percentile: Top 72%
Advanced Radiotherapy Techniques
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