Efficacy and safety of cinobufacini capsules combined with oxaliplatin-based chemotherapy for advanced colorectal cancer: a human systematic review and meta-analysis
Cinobufacini combined with oxaliplatin-based chemotherapy may enhance short-term efficacy, immune function, and safety in advanced CRC. However, due to limitations of existing RCTs, these findings should be interpreted cautiously, and further large-scale, high-quality trials are required.
Authors
- Da Zheng (ORCID: https://orcid.org/0000-0003-3013-0722)
- Qile Gao (ORCID: https://orcid.org/0000-0002-0239-9508)
- Jian Wang (ORCID: https://orcid.org/0000-0002-1278-256X)
- Yangming Que
- Jianxin Chen
Institutions
- Changsha Medical University (CN)
- Quzhou City People's Hospital (CN)
- Taizhou Second People's Hospital (CN)
- Quzhou University (CN)
- First Hospital of Jiaxing (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2026-01-30
- DOI
- https://doi.org/10.3389/fphar.2026.1709044
- Primary Topic
- Bioactive Compounds and Antitumor Agents
- Type
- article
- Field-Weighted Citation Impact
- 0.00