Biological Mechanisms of Strength Preservation During Calorie Restriction-Induced Weight Loss Among Young- to Middle-Aged Adults without Obesity

These findings highlight molecular pathways supporting strength retention during CR-induced weight loss. Heat-shock protein, <i>HSP90AA1</i>, warrants further investigation as a candidate target for preserving muscle strength during interventions aimed at weight reduction.

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Publication Details

Journal
bioRxiv (Cold Spring Harbor Laboratory)
Published
2026-01-30
DOI
https://doi.org/10.64898/2026.01.29.702632
Primary Topic
Dietary Effects on Health
Type
article
Field-Weighted Citation Impact
0.00
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article

Biological Mechanisms of Strength Preservation During Calorie Restriction-Induced Weight Loss Among Young- to Middle-Aged Adults without Obesity

Katherine A. Collins, Leanna M. Ross, Paula G. Miller, Susan B. Racette et al.
bioRxiv (Cold Spring Harbor Laboratory)
Dietary Effects on Health
article

Biological Mechanisms of Strength Preservation During Calorie Restriction-Induced Weight Loss Among Young- to Middle-Aged Adults without Obesity

Katherine A. Collins, Leanna M. Ross, Paula G. Miller, Susan B. Racette, Kim Huffman, Nadia Moore, Akshay Bareja, Sai Krupa Das, Leanne M Redman, Corby K Martin
article en

Abstract

These findings highlight molecular pathways supporting strength retention during CR-induced weight loss. Heat-shock protein, <i>HSP90AA1</i>, warrants further investigation as a candidate target for preserving muscle strength during interventions aimed at weight reduction.

bioRxiv (Cold Spring Harbor Laboratory)
Pennington Biomedical Research Center (US), Tufts University (US), Duke University (US), Jean Mayer Human Nutrition Research Center on Aging (US), Arizona State University (US)
Openalex Percentile: Top 71%
Dietary Effects on Health
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