High‐mobility Group Protein 1/ Receptor for Advanced Glycation End Products/ Nuclear Factor‐κB Signalling Pathway Contributes to the Pathogenic Process of Striatal Neuron Impairment in the Rat Model of Parkinson's Disease
The HMGB1/RAGE/NF-κB signaling pathway plays a critical role in the pathogenesis of striatal neuronal damage in PD, highlighting its potential as a therapeutic target.
Authors
- Wanlong Lei (ORCID: https://orcid.org/0000-0002-7309-2722)
- Linju Jia
- Li Sun (ORCID: https://orcid.org/0000-0002-2454-741X)
- Xuefeng Zheng (ORCID: https://orcid.org/0000-0002-3800-8628)
- Yaofeng Zhu
- Zean Du
- Ziyun Huang (ORCID: https://orcid.org/0009-0009-3899-6441)
- Tao Chen
Institutions
- Jishou University (CN)
- Sun Yat-sen University (CN)
- Jinan University (CN)
- Sixth Affiliated Hospital of Sun Yat-sen University (CN)
Publication Details
- Journal
- Brain and Behavior
- Published
- 2026-01-29
- DOI
- https://doi.org/10.1002/brb3.71133
- Primary Topic
- Advanced Glycation End Products research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Sun Yat-sen University
- Natural Science Foundation of Hunan Province
- Basic and Applied Basic Research Foundation of Guangdong Province