COMPARATIVE ANTIMICROBIAL STUDY OF ROHINYADI PACHANA KWATHA AND ROHINYADI PACHANA ARISHTA

Introduction: Diarrhoea is defined as the passage of loose, liquid or watery stools. These liquid stools are usually passed more than three times a day. In diarrhoea ion channels and exchangers in epithelial cells can promote intestinal secretion, thereby enhancing gastrointestinal transit and promoting faecal excretion. Atisaara, one of the diseases mentioned in Ayurvedic Classics has its cardinal feature as frequency of loose stools which mimics the Diarrhoeal symptoms. Kwatha should be prepared and used instantly as it has limited shelf life. On the other hand, Arishta has prolonged shelf life, considering these factors, present study is planned to prepare Rohinyadi Paachana Arista from Rohinyadi Paachana Kwatha, for evaluation and validation of antimicrobial properties of two dosage forms on bacteria such as Salmonella sp., Shigella flexneri and Escherichia coli. Methodology: In antibacterial study by agar well diffusion method, the zone of inhibition of both the sample were tested against three bacteria namely Salmonella enterica, Shigella flexneri and Escherichia coli. Result: Rohinyadi Pachana Arishta exhibited zone of inhibition against all three tested organisms at all concentration. Rohinyadi Pachana Kashaya exhibited the zone of inhibition against Shigella flexneri.