Heart ventricular function in hospitalized patients with severe hypothyroidism and myxedema coma
Severe hypothyroidism is associated with frequent systolic and diastolic ventricular dysfunction and prevalent impairment of myocardial deformation. Associations between cardiovascular medication exposure and echocardiographic abnormalities likely reflect confounding by indication and underlying clinical phenotype rather than reflecting causal drug effects. Despite substantial myocardial abnormalities, short-term mortality was low.
Authors
- Shourya Tadisina (ORCID: https://orcid.org/0009-0003-9612-0014)
- Khalid Al-Zubaidi
- Ty Whisenant
- Aliakbar Arvandi
- Patricia Pérez-Castro
- Prasanth Surampudi
- Irsa Munir
- Yang K. Xiang (ORCID: https://orcid.org/0000-0003-1786-9143)
- Aili Guo
- Thomas W. Smith (ORCID: https://orcid.org/0000-0002-7987-5672)
- Eva Fernández-Rodríguez (ORCID: https://orcid.org/0000-0003-3234-1486)
- Rajib Bhattacharya
- Sobrina Sarah Mohammed
- Miranda Stiewig-Rapp
- Antia Fernandez-Pombo
- Maria Jose Ginzo-Villamayor
- Cristina Tejera-Perez
Institutions
- Universidade da Coruña (ES)
- Texas Tech University (US)
- Universidade de Santiago de Compostela (ES)
- Truman Medical Center (US)
- University Hospital Complex Of Vigo (ES)
- University of California Davis Medical Center (US)
- Complejo Hospitalario de Ourense (ES)
- Universidade de Vigo (ES)
- University of California, Davis (US)
- Texas Tech University Health Sciences Center (US)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2026-01-28
- DOI
- https://doi.org/10.1210/clinem/dgag036
- Primary Topic
- Thyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00