Vitamin D3 mediates amelioration of ulcerative colitis via the TRPV1-MAPK signaling pathway

This study elucidates a protective role of VD3 in UC, whereby it coordinately regulates immune responses and barrier function via the TRPV1-MAPK signaling pathway, providing a novel theoretical and experimental foundation for VD3-based therapy for UC.

Authors

Wensong Ge
Keke Zhao
Yersen Asai
Longxiang Zhang
Jian Li
Ziying Hu

Institutions

Xinjiang Medical University (CN)
First Affiliated Hospital of Xinjiang Medical University (CN)

Publication Details

Journal: Frontiers in Immunology
Published: 2026-01-30
DOI: https://doi.org/10.3389/fimmu.2026.1727932
Primary Topic: Vitamin D Research Studies
Type: article
Field-Weighted Citation Impact: 0.00

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article

Vitamin D3 mediates amelioration of ulcerative colitis via the TRPV1-MAPK signaling pathway

Wensong Ge, Keke Zhao, Yersen Asai, Longxiang Zhang et al.

Jan 30, 2026

Frontiers in Immunology

Vitamin D Research Studies

article

Vitamin D3 mediates amelioration of ulcerative colitis via the TRPV1-MAPK signaling pathway

Wensong Ge, Keke Zhao, Yersen Asai, Longxiang Zhang, Jian Li, Ziying Hu

January 30, 2026article en

Abstract

Frontiers in ImmunologyVol. 17

Xinjiang Medical University (CN), First Affiliated Hospital of Xinjiang Medical University (CN)

Good health and well-being

Openalex Percentile: Top 73%

Vitamin D Research Studies

DOI Open Access PDF OpenAlex

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