Survival Benefit of Adjuvant Radiotherapy After Surgery in Patients With <scp>T1</scp> ‐ <scp>2N1M0</scp> Hypopharyngeal Squamous Cell Carcinoma: A Dual‐Cohort Analysis of <scp>SEER</scp> and Institutional Data

There was no significant difference in OS in patients with T2-3N0-3 M0 or T1N1-3 M0 HPSCC according to whether or not they underwent surgery as first-line treatment. Surgery plus postoperative radiotherapy was associated with a more favorable prognosis than surgery alone in patients with T1-2N1M0 HPSCC.

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Publication Details

Journal
Cancer Medicine
Published
2026-01-30
DOI
https://doi.org/10.1002/cam4.71555
Primary Topic
Head and Neck Cancer Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Survival Benefit of Adjuvant Radiotherapy After Surgery in Patients With T1 ‐ 2N1M0 Hypopharyngeal Squamous Cell Carcinoma: A Dual‐Cohort Analysis of SEER and Institutional Data

Wenbin Lei, Renqiang Ma, Yihui Wen, Jie Deng et al.
Cancer Medicine
Head and Neck Cancer Studies
article

Survival Benefit of Adjuvant Radiotherapy After Surgery in Patients With T1 ‐ 2N1M0 Hypopharyngeal Squamous Cell Carcinoma: A Dual‐Cohort Analysis of SEER and Institutional Data

Wenbin Lei, Renqiang Ma, Yihui Wen, Jie Deng, Weiping Wen, Zhangwei Hu, Wei Sun, Lin Chen
article en

Abstract

There was no significant difference in OS in patients with T2-3N0-3 M0 or T1N1-3 M0 HPSCC according to whether or not they underwent surgery as first-line treatment. Surgery plus postoperative radiotherapy was associated with a more favorable prognosis than surgery alone in patients with T1-2N1M0 HPSCC.

Cancer MedicineVol. 15(2)
Sun Yat-sen University (CN), Sixth Affiliated Hospital of Sun Yat-sen University (CN), The First Affiliated Hospital, Sun Yat-sen University (CN)
National Natural Science Foundation of China, Sun Yat-sen University, China Postdoctoral Science Foundation, Basic and Applied Basic Research Foundation of Guangdong Province
Good health and well-being
Openalex Percentile: Top 72%
Head and Neck Cancer Studies
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