Surgical treatment of myxopapillary ependymoma: an institutional case series of 56 patients
MPEs are benign tumors that arise predominantly from the filum terminale. Resection can be curative, especially for well-marginated tumors arising from the proximal filum terminale. Despite their benign nature, the tumors' lack of a capsule, friable tumor consistency, and frequent direct contact with the CSF and cauda equina create a propensity for local recurrence and CSF dissemination, especially for larger and distally originating tumors. Thus, long-term follow-up is recommended for all patients as is early surgical intervention for small, incidental MPEs.
Authors
- Christopher E. Mandigo (ORCID: https://orcid.org/0000-0002-9676-5205)
- Justin A. Neira
- Jane Kostadinov
- Phoebe Greenwald (ORCID: https://orcid.org/0009-0006-0567-9755)
- Peter D. Angevine (ORCID: https://orcid.org/0000-0003-1468-8611)
- Alexander G. Khandji
- Evan F Joiner
- Andrew K Chan
- Paul C McCormick
Institutions
- Seattle Children's Hospital (US)
- University of Washington (US)
- New York Hospital Queens (US)
- Presbyterian Hospital (US)
Publication Details
- Journal
- Journal of Neurosurgery Spine
- Published
- 2026-01-30
- DOI
- https://doi.org/10.3171/2025.9.spine25650
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00