Resveratrol inhibits bladder cancer proliferation by targeting the AURKA/STAT3 axis: From computational analysis to experimental validation

Our findings suggest that Res may regulate BCa cell expression through the AURKA/STAT3 axis, providing a theoretical foundation for the structural optimization of Res and the development of multi-target drugs for clinical application.

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Publication Details

Journal
PLoS ONE
Published
2026-01-30
DOI
https://doi.org/10.1371/journal.pone.0342162
Primary Topic
Sirtuins and Resveratrol in Medicine
Type
article
Field-Weighted Citation Impact
0.00

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article

Resveratrol inhibits bladder cancer proliferation by targeting the AURKA/STAT3 axis: From computational analysis to experimental validation

WenXin Ye, J. Chen, Yan Shu, Ligang Ren et al.
PLoS ONE
Sirtuins and Resveratrol in Medicine
article

Resveratrol inhibits bladder cancer proliferation by targeting the AURKA/STAT3 axis: From computational analysis to experimental validation

WenXin Ye, J. Chen, Yan Shu, Ligang Ren, Guodong Chen, Chao Feng
article en

Abstract

Our findings suggest that Res may regulate BCa cell expression through the AURKA/STAT3 axis, providing a theoretical foundation for the structural optimization of Res and the development of multi-target drugs for clinical application.

PLoS ONEVol. 21(1)
Tongde Hospital of Zhejiang Province (CN)
Science and Technology Program of Zhejiang Province
Good health and well-being
Openalex Percentile: Top 73%
Sirtuins and Resveratrol in Medicine
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