The effect of glucagon-like peptide 1 (GLP-1) receptor agonists on cognition: A systematic review of systematic reviews and meta-analyses

GLP-1 RAs positively affect cognitive function in AD patients with T2DM. However, their efficacy on disparate cognitive domains requires further replication in larger scale controlled clinical trials.

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Publication Details

Journal
Journal of Affective Disorders
Published
2026-01-30
DOI
https://doi.org/10.1016/j.jad.2026.121310
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

The effect of glucagon-like peptide 1 (GLP-1) receptor agonists on cognition: A systematic review of systematic reviews and meta-analyses

Hana Ballum, Sonya Liao, Christine E. Dri, Gia Han Le et al.
Journal of Affective Disorders
Diabetes Treatment and Management
article

The effect of glucagon-like peptide 1 (GLP-1) receptor agonists on cognition: A systematic review of systematic reviews and meta-analyses

Hana Ballum, Sonya Liao, Christine E. Dri, Gia Han Le, Kayla M. Teopiz, Hayun Choi, Heidi K.Y.Lo, Minyi Yu, Roger S. McIntyre, Maj Vinberg, Joshua D. Rosenblat, Angela T.H. Kwan, Roger Ho, Sabrina Wong
article en

Abstract

GLP-1 RAs positively affect cognitive function in AD patients with T2DM. However, their efficacy on disparate cognitive domains requires further replication in larger scale controlled clinical trials.

Journal of Affective DisordersVol. 402
Chinese University of Hong Kong (HK), University of Toronto (CA), Hong Kong University of Science and Technology (HK), Brain and Cognition Discovery Foundation (CA), Capital Region of Denmark (DK), University of Hong Kong (HK)
Openalex Percentile: Top 74%
Diabetes Treatment and Management
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