Efficacy and Safety of Letrozole, Misoprostol and Their Combination in First Trimester Missed Miscarriage: <i>A randomised clinical trial</i>
Combining letrozole with misoprostol significantly improves complete miscarriage rates with tolerable safety. Letrozole alone is safer but less effective. Thus, combination therapy may offer an optimal non-surgical strategy for individualised management.
Authors
- Mohamed Mohamed
- Ahmed Hassan
- Abdelrahman Adel Abdelmonem Salama
- Mohamed Fikry Yousef
- Hany Saad Amin Mohamed
- Ahmed Ragab Ebrahim Ragab
- Mamdouh Abdelfatah Sheeba
- Mahmoud Mostafa Hassan Ali
- Amira Alasmer
- Marwan Taghian
Institutions
- NHS Lothian (GB)
- Cairo University (EG)
- Al-Azhar University (EG)
- Columbia University Irving Medical Center (US)
- October 6 University (EG)
Publication Details
- Journal
- Sultan Qaboos University medical journal
- Published
- 2026-01-29
- DOI
- https://doi.org/10.18295/2075-0528.2962
- Primary Topic
- Reproductive System and Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 0.00