Selective Inhibition of Protein Kinase D2 Activity Reduces Human Neutrophil Survival

PKD2 plays a crucial role in human neutrophil survival. Minimizing PKD2 inhibition during small-molecule drug design could be essential to reduce the risk of neutropenia in patients under anti-cancer treatment.

Authors

Noriko Uchiyama (ORCID: https://orcid.org/0000-0003-4042-1574)

Institutions

Takeda (Japan) (JP)

Publication Details

Journal: Anticancer Research
Published: 2026-01-30
DOI: https://doi.org/10.21873/anticanres.17977
Primary Topic: Blood disorders and treatments
Type: article
Field-Weighted Citation Impact: 0.00

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article

Selective Inhibition of Protein Kinase D2 Activity Reduces Human Neutrophil Survival

Noriko Uchiyama

Jan 30, 2026

Anticancer Research

Blood disorders and treatments

article

Selective Inhibition of Protein Kinase D2 Activity Reduces Human Neutrophil Survival

Noriko Uchiyama

January 30, 2026article en

Abstract

Anticancer ResearchVol. 46(2)

Takeda (Japan) (JP)

Good health and well-being

Openalex Percentile: Top 68%

Blood disorders and treatments

DOI Source OpenAlex

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Selective Inhibition of Protein Kinase D2 Activity Reduces Human Neutrophil Survival — Noriko Uchiyama · Anticancer Research (2026) | TGRS Research Map | TGRS