Pharmacological interventions for alcohol use disorder: novel insights from recent clinical trials

Adopting a precision medicine approach and investigating novel compounds for AUD treatment requires a shift in systems of care. Precision medicine navigates away from the traditional 'one size fits all' health care model to emphasize the individual, leading to long-term cost-effectiveness and improved patient outcomes. Moreover, novel pharmacotherapies face challenges in the scale of their distribution throughout healthcare settings. The developments reviewed in this paper elucidate a paradigm shift necessary to facilitate the integration of precision medicine and the adoption of novel pharmacotherapies within the AUD field.

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Publication Details

Journal
Expert Review of Clinical Pharmacology
Published
2026-01-30
DOI
https://doi.org/10.1080/17512433.2026.2625341
Primary Topic
Substance Abuse Treatment and Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

Pharmacological interventions for alcohol use disorder: novel insights from recent clinical trials

Kaitlin R. McManus, Lara A. Ray
Expert Review of Clinical Pharmacology
Substance Abuse Treatment and Outcomes
article

Pharmacological interventions for alcohol use disorder: novel insights from recent clinical trials

Kaitlin R. McManus, Lara A. Ray
article en

Abstract

Adopting a precision medicine approach and investigating novel compounds for AUD treatment requires a shift in systems of care. Precision medicine navigates away from the traditional 'one size fits all' health care model to emphasize the individual, leading to long-term cost-effectiveness and improved patient outcomes. Moreover, novel pharmacotherapies face challenges in the scale of their distribution throughout healthcare settings. The developments reviewed in this paper elucidate a paradigm shift necessary to facilitate the integration of precision medicine and the adoption of novel pharmacotherapies within the AUD field.

Expert Review of Clinical PharmacologyVol. 19(2)
University of California System (US)
Good health and well-being
Openalex Percentile: Top 71%
Substance Abuse Treatment and Outcomes
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Pharmacological interventions for alcohol use disorder: novel insights from recent clinical trials — Kaitlin R. McManus, Lara A. Ray · Expert Review of Clinical Pharmacology (2026) | TGRS Research Map | TGRS