<i>POM121</i> Drives Gastric Cancer Progression <i>via</i> the mTOR/p70S6K Signaling Axis

<i>POM121</i> promotes GC progression by enhancing proliferative and invasive phenotypes through p70S6 kinase-mediated signaling. These findings establish <i>POM121</i> as a novel oncogene, prognostic biomarker, and potential therapeutic target in GC.

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Publication Details

Journal
Anticancer Research
Published
2026-01-30
DOI
https://doi.org/10.21873/anticanres.17987
Primary Topic
PI3K/AKT/mTOR signaling in cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

POM121 Drives Gastric Cancer Progression via the mTOR/p70S6K Signaling Axis

Hong-Beum Kim, Sang-Gon Park, HEE-JEONG LEE, SEONG-HUN KIM et al.
Anticancer Research
PI3K/AKT/mTOR signaling in cancer
article

POM121 Drives Gastric Cancer Progression via the mTOR/p70S6K Signaling Axis

Hong-Beum Kim, Sang-Gon Park, HEE-JEONG LEE, SEONG-HUN KIM, Hye-Hwa Lee
article en

Abstract

<i>POM121</i> promotes GC progression by enhancing proliferative and invasive phenotypes through p70S6 kinase-mediated signaling. These findings establish <i>POM121</i> as a novel oncogene, prognostic biomarker, and potential therapeutic target in GC.

Anticancer ResearchVol. 46(2)
Chosun University (KR), Chosun University Hospital (KR)
Good health and well-being
Openalex Percentile: Top 73%
PI3K/AKT/mTOR signaling in cancer
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