Aberrant Mobility Disorder in an Uncontrolled Type 2 Diabetic – A Case Report on Diabetic Striatopathy

We report a 55-year-old female who presented with choreiform movements in the right upper and lower limbs and uncontrolled blood sugar levels. Magnetic resonance imaging (MRI) of the brain revealed hyperdense lesions, without diffusion restriction or blooming on gradient echo, in the left lentiform and caudate nuclei. The clinical presentation and MRI brain findings pointed towards a diagnosis of diabetic striatopathy (DS). DS, an underrecognized and underdiagnosed condition, primarily affects older women with poorly-managed diabetes mellitus. Effective management of this disorder chiefly depends on maintaining optimal blood glucose levels. After rigorous glycemic control using insulin therapy, the patient's symptoms started to improve, achieving complete remission of symptoms in about a month.

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Publication Details

Journal
Annals of African Medicine
Published
2026-01-29
DOI
https://doi.org/10.4103/aam.aam_523_25
Primary Topic
Neurological and metabolic disorders
Type
article
Field-Weighted Citation Impact
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article

Aberrant Mobility Disorder in an Uncontrolled Type 2 Diabetic – A Case Report on Diabetic Striatopathy

Sanket Genuji Shinde, Satbir Kaur Malik, Sangram Mangudkar, Divam Prakash Singh
Annals of African Medicine
Neurological and metabolic disorders
article

Aberrant Mobility Disorder in an Uncontrolled Type 2 Diabetic – A Case Report on Diabetic Striatopathy

Sanket Genuji Shinde, Satbir Kaur Malik, Sangram Mangudkar, Divam Prakash Singh
article en

Abstract

We report a 55-year-old female who presented with choreiform movements in the right upper and lower limbs and uncontrolled blood sugar levels. Magnetic resonance imaging (MRI) of the brain revealed hyperdense lesions, without diffusion restriction or blooming on gradient echo, in the left lentiform and caudate nuclei. The clinical presentation and MRI brain findings pointed towards a diagnosis of diabetic striatopathy (DS). DS, an underrecognized and underdiagnosed condition, primarily affects older women with poorly-managed diabetes mellitus. Effective management of this disorder chiefly depends on maintaining optimal blood glucose levels. After rigorous glycemic control using insulin therapy, the patient's symptoms started to improve, achieving complete remission of symptoms in about a month.

Annals of African Medicine
Dr. D. Y. Patil Medical College, Hospital and Research Centre (IN), Dr. D.Y. Patil Vidyapeeth, Pune (IN)
Gender equality
Openalex Percentile: Top 74%
Neurological and metabolic disorders
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