Nanobody MET CAR-T cells show efficacy in solid tumors
With the multiple advantages of VHHs including small size, stability, and low potential for tonic signaling, VHH-CAR-T cells represent a promising approach for CAR-T design against solid tumors.
Authors
- Jon S. Morrow
- Qin Yan (ORCID: https://orcid.org/0000-0002-3974-0298)
- Arnaud Augert
- Sam Devereaux
- Danielle Sohai
- Samuel G. Katz (ORCID: https://orcid.org/0000-0003-1744-8568)
- Yong Li (ORCID: https://orcid.org/0000-0003-4038-0493)
- Michael C. Stankewich
- Mileena T. Nguyen
- Qin Li
- Po‐Han Chen (ORCID: https://orcid.org/0000-0002-9471-4471)
- Pan Cha
- Nancy Chen
- Rianna Raghunandan
Institutions
- Yale Cancer Center (US)
- Yale University (US)
- University College London (GB)
Publication Details
- Journal
- bioRxiv (Cold Spring Harbor Laboratory)
- Published
- 2026-01-30
- DOI
- https://doi.org/10.64898/2026.01.27.702111
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.00