Cardiac Lymphatics Predict Survival After Heart Transplantation

These findings indicate a potential association between reduced lymphatics and CAV, where upon further validation lymphatic area might serve as a measurable parameter to identify patients at risk for CAV and mortality. Because the survival analysis included limited adjustments, additional studies will be needed to incorporate key clinical confounders capable of influencing the relationship between lymphatic development and OHT outcomes. Future studies should investigate the mechanistic link between cardiac lymphatics and CAV and if lymphangiogenic pathways have therapeutic potential to improve OHT outcomes.