Fully validated HPLC-UV detection method associated with colour variation control for evaluation of the stability of 5-fluorouracil chemotherapy polyolefin infusion bags at dose banding
A stability-indicating HPLC method was developed to determine 5-FU concentrations in dose-banding conditions associated with colour variation investigations. This study supports a centralised production of 5-FU at standardised dose banding.
Authors
- Lydie Lethier (ORCID: https://orcid.org/0000-0001-6768-8004)
- Yves Claude Guillaume
- Claire André
Institutions
- Centre Hospitalier Universitaire de Besançon (FR)
- Université Bourgogne Franche-Comté (FR)
- Institut Supérieur des Beaux-arts de Besançon (FR)
- Université de Franche-Comté (FR)
Publication Details
- Journal
- European Journal of Hospital Pharmacy
- Published
- 2026-01-30
- DOI
- https://doi.org/10.1136/ejhpharm-2025-004739
- Primary Topic
- Safe Handling of Antineoplastic Drugs
- Type
- article
- Field-Weighted Citation Impact
- 0.00