Combined Aspirin Study for Mechanical Prosthetic Valve in Kyushu and Ryukyu by Inter-University Hospital Network (ASPIRIN-Trial)
Adding aspirin to warfarin treatment was not superior to warfarin alone, and relatively weak warfarin treatment (PT-INR <2.0) was not necessarily associated with an increased number of events (vs. PT-INR 2.0-3.0) in Japanese patients who underwent MeVR.
Authors
- Takashi Shuto (ORCID: https://orcid.org/0000-0002-7150-4519)
- Kunihide Nakamura
- Masanori Takamatsu
- Jun Takaki
- Y. Otsuji
- Yuya Kise
- Hideichi Wada
- Hiroyuki Morokuma (ORCID: https://orcid.org/0000-0002-7967-773X)
- Yoshiharu Soga (ORCID: https://orcid.org/0000-0001-6718-6960)
- Kojiro Furukawa
- Kazuyoshi Takagi
- Takayuki Kawashima (ORCID: https://orcid.org/0000-0003-1631-8497)
- Hiromitsu Teratani
- Hitoshi Inafuku
- Shinji Miyamoto
- Go Kuwahara
- Koichi Arinaga
- Takashi Yoshinaga
- Toru Yasutsune
- YUKI TSUDA
- Shuhei Sakaguchi
- T Miura
- Hideaki Kanda
- Keiji Kamohara (ORCID: https://orcid.org/0009-0006-1277-4494)
- Yosuke Nishimura
- Tomoki Ushijima
- Yoshihisa Fujino
- Eiki Tayama
- Hiromichi Sonoda
- Kiyoyuki Eishi
- on behalf of the ASPIRIN-Trial Investigators
- Akira Shiose
- Ichiro Matsumaru
- Toshihiro Fukui
- Koji Furukawa
- Masataka Eto
Institutions
- Kurume University (JP)
- Kagoshima University (JP)
- University of Miyazaki (JP)
- Kyushu University (JP)
- Saga University (JP)
- University of Occupational and Environmental Health Japan (JP)
- Oita University (JP)
- Fukuoka University (JP)
- University of the Ryukyus University Hospital (JP)
- Nagasaki University (JP)
- Kumamoto University (JP)
Publication Details
- Journal
- Circulation Journal
- Published
- 2026-01-30
- DOI
- https://doi.org/10.1253/circj.cj-25-0460
- Citations
- 1
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 30.07
Funders
- University of Occupational and Environmental Health