Development and Validation of the Predicting Risk of Ischemic Stroke in Malignancy Estimation Tool

We derived and validated the PRIME (Predicting Risk of Ischemic Stroke in Malignancy Estimation) tool with good discrimination for ischemic stroke in patients with a new cancer diagnosis. The model was built into an online calculator (https://study.ohri.ca/PRIME/) and has the potential to stratify patients with cancer based on their risk of stroke within a year following their diagnosis.

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Publication Details

Journal
Journal of the American Heart Association
Published
2026-01-30
DOI
https://doi.org/10.1161/jaha.125.045631
Citations
1
Primary Topic
Acute Ischemic Stroke Management
Type
article
Field-Weighted Citation Impact
31.52
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article

Development and Validation of the Predicting Risk of Ischemic Stroke in Malignancy Estimation Tool

Moira K. Kapral, David H. Kirkwood, Jenneke Leentjens, Ronda Lun et al.
1 citations
Journal of the American Heart Association
Acute Ischemic Stroke Management
31.52
article

Development and Validation of the Predicting Risk of Ischemic Stroke in Malignancy Estimation Tool

Moira K. Kapral, David H. Kirkwood, Jenneke Leentjens, Ronda Lun, Joshua O. Cerasuolo, Marc Carrier, Deborah Siegal
article en
1 citations

Abstract

We derived and validated the PRIME (Predicting Risk of Ischemic Stroke in Malignancy Estimation) tool with good discrimination for ischemic stroke in patients with a new cancer diagnosis. The model was built into an online calculator (https://study.ohri.ca/PRIME/) and has the potential to stratify patients with cancer based on their risk of stroke within a year following their diagnosis.

Journal of the American Heart AssociationVol. 15(3)
Radboud University Nijmegen (NL), University of Ottawa (CA), University of Calgary (CA), University of Toronto (CA), Ottawa Hospital (CA), University Medical Center (US), Radboud University Medical Center (NL), Ottawa Hospital Research Institute (CA), McMaster University (CA)
Reduced inequalities
Openalex Percentile: Top 1%
Acute Ischemic Stroke Management
31.52
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