Circulating Cytotoxic T Lymphocytes Associated Antigen-4 (CTLA-4) Levels and CTLA-4 Gene Polymorphism Role in Head and Neck Squamous Cell Carcinoma

Conclusions: The G allele and the heterozygous genotype (AG) may be regarded as protective factors from HNSCC, and AA genotype is risk factor for HNSCC. Soluble CTLA-4 rise remarkably in patients with HNSCC suggesting a function for this protein in pathogenesis of this disease.

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Wiadomości Lekarskie
Published
2025-12-30
DOI
https://doi.org/10.36740/wlek/214629
Primary Topic
Diabetes and associated disorders
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article
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article

Circulating Cytotoxic T Lymphocytes Associated Antigen-4 (CTLA-4) Levels and CTLA-4 Gene Polymorphism Role in Head and Neck Squamous Cell Carcinoma

Awf Abdulrahman Sulaiman, Rafal Khaleel Farhan, Yaala Saady Raof, Hiba Hadi Rashid
Wiadomości Lekarskie
Diabetes and associated disorders
article

Circulating Cytotoxic T Lymphocytes Associated Antigen-4 (CTLA-4) Levels and CTLA-4 Gene Polymorphism Role in Head and Neck Squamous Cell Carcinoma

Awf Abdulrahman Sulaiman, Rafal Khaleel Farhan, Yaala Saady Raof, Hiba Hadi Rashid
article en

Abstract

Conclusions: The G allele and the heterozygous genotype (AG) may be regarded as protective factors from HNSCC, and AA genotype is risk factor for HNSCC. Soluble CTLA-4 rise remarkably in patients with HNSCC suggesting a function for this protein in pathogenesis of this disease.

Wiadomości LekarskieVol. 78(12)
Baghdad Medical City (IQ), University of Al Maarif (IQ), University of Tikrit (IQ), University of Diyala (IQ)
Sustainable cities and communities
Openalex Percentile: Top 22%
Diabetes and associated disorders
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