Delayed complete atrioventricular block 11 months after transcatheter aortic valve replacement in a patient with a short membranous septum: a case report

Conduction disturbances are among the most frequent complications of transcatheter aortic valve replacement (TAVR), typically occurring within the first 72 h after implantation. However, delayed complete atrioventricular (AV) block is rare and may present late with serious clinical consequences. We describe the case of a 72-year-old man with hypertension who developed complete AV block nearly 1 year after TAVR, underscoring the importance of long-term surveillance in patients with high-risk anatomy. The patient initially presented with progressive exertional dyspnea and was diagnosed with severe low-flow, low-gradient aortic stenosis, with a left ventricular ejection fraction of 33%. Preprocedural computed tomography demonstrated a short membranous septum (4.0 mm) and an annulus-membranous septum distance of 1.2 mm, both of which are recognized predictors of conduction disturbances. He underwent transfemoral TAVR with a self-expanding Qiming L26 valve implanted at a depth of approximately 5 mm. Early recovery was uneventful, aside from a small paravalvular leak, which resolved by the 8-month follow-up, at which time echocardiography showed recovery of systolic function to 60%, and sinus rhythm was observed on electrocardiography. At 11 months following TAVR, a community screening ECG revealed 2:1 AV block, and 3 weeks later, he presented with symptomatic complete AV block and a ventricular escape rhythm at 30 bpm. Repeat CT showed increased frame depth (7.6 and 9.8 mm), suggesting possible valve-septum interaction; however, causal attribution is limited by the absence of immediate/serial CT and electrophysiological mapping, and age-related conduction system disease may have contributed to this finding. A dual-chamber permanent pacemaker was implanted, resulting in complete symptomatic recovery and a stable prosthetic valve function. This case report highlights a rare but clinically important phenomenon of very late conduction block after TAVR and supports a risk-stratified approach to anatomical assessment and long-term rhythm monitoring. However, this inference remains hypothesis-generating, given its single-patient nature.

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Journal
Frontiers in Cardiovascular Medicine
Published
2026-01-30
DOI
https://doi.org/10.3389/fcvm.2026.1703981
Citations
1
Primary Topic
Cardiac Valve Diseases and Treatments
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article
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30.07
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article

Delayed complete atrioventricular block 11 months after transcatheter aortic valve replacement in a patient with a short membranous septum: a case report

Zheng Cao, Zhixiao Wang, Djandan Tadum Arthur Vithran, Jian Xiong et al.
1 citations
Frontiers in Cardiovascular Medicine
Cardiac Valve Diseases and Treatments
30.07
article

Delayed complete atrioventricular block 11 months after transcatheter aortic valve replacement in a patient with a short membranous septum: a case report

Zheng Cao, Zhixiao Wang, Djandan Tadum Arthur Vithran, Jian Xiong, Xiaoyong Hu
article en
1 citations

Abstract

Conduction disturbances are among the most frequent complications of transcatheter aortic valve replacement (TAVR), typically occurring within the first 72 h after implantation. However, delayed complete atrioventricular (AV) block is rare and may present late with serious clinical consequences. We describe the case of a 72-year-old man with hypertension who developed complete AV block nearly 1 year after TAVR, underscoring the importance of long-term surveillance in patients with high-risk anatomy. The patient initially presented with progressive exertional dyspnea and was diagnosed with severe low-flow, low-gradient aortic stenosis, with a left ventricular ejection fraction of 33%. Preprocedural computed tomography demonstrated a short membranous septum (4.0 mm) and an annulus-membranous septum distance of 1.2 mm, both of which are recognized predictors of conduction disturbances. He underwent transfemoral TAVR with a self-expanding Qiming L26 valve implanted at a depth of approximately 5 mm. Early recovery was uneventful, aside from a small paravalvular leak, which resolved by the 8-month follow-up, at which time echocardiography showed recovery of systolic function to 60%, and sinus rhythm was observed on electrocardiography. At 11 months following TAVR, a community screening ECG revealed 2:1 AV block, and 3 weeks later, he presented with symptomatic complete AV block and a ventricular escape rhythm at 30 bpm. Repeat CT showed increased frame depth (7.6 and 9.8 mm), suggesting possible valve-septum interaction; however, causal attribution is limited by the absence of immediate/serial CT and electrophysiological mapping, and age-related conduction system disease may have contributed to this finding. A dual-chamber permanent pacemaker was implanted, resulting in complete symptomatic recovery and a stable prosthetic valve function. This case report highlights a rare but clinically important phenomenon of very late conduction block after TAVR and supports a risk-stratified approach to anatomical assessment and long-term rhythm monitoring. However, this inference remains hypothesis-generating, given its single-patient nature.

Frontiers in Cardiovascular MedicineVol. 13
Hubei University of Medicine (CN), Central South University (CN), Second Affiliated Hospital of Zhengzhou University (CN), Xiangya Hospital Central South University (CN)
Good health and well-being
Openalex Percentile: Top 2%
Cardiac Valve Diseases and Treatments
30.07
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