Evaluation of the Nephroprotective Effect of Dibenzazepin γ-secretase inhibitor on Renal Ischemia Reperfusion Injury in Male Rats

Conclusions: DBZ (γ-secretase inhibitor) has considerable nephroprotective benefits in renal IRI via inhibiting the Notch pathway, anti-apoptotic, antioxidant, and anti-inflammatory effect.

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Publication Details

Journal
Wiadomości Lekarskie
Published
2025-12-30
DOI
https://doi.org/10.36740/wlek/214631
Primary Topic
Acute Kidney Injury Research
Type
article
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article

Evaluation of the Nephroprotective Effect of Dibenzazepin γ-secretase inhibitor on Renal Ischemia Reperfusion Injury in Male Rats

Qayssar Joudah Fadheel, Zahraa I. J. Shubber
Wiadomości Lekarskie
Acute Kidney Injury Research
article

Evaluation of the Nephroprotective Effect of Dibenzazepin γ-secretase inhibitor on Renal Ischemia Reperfusion Injury in Male Rats

Qayssar Joudah Fadheel, Zahraa I. J. Shubber
article en

Abstract

Conclusions: DBZ (γ-secretase inhibitor) has considerable nephroprotective benefits in renal IRI via inhibiting the Notch pathway, anti-apoptotic, antioxidant, and anti-inflammatory effect.

Wiadomości LekarskieVol. 78(12)
University of Babylon (IQ), Alsalam University College (IQ)
Good health and well-being
Openalex Percentile: Top 26%
Acute Kidney Injury Research
DOIOpen Access PDFOpenAlex
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Evaluation of the Nephroprotective Effect of Dibenzazepin γ-secretase inhibitor on Renal Ischemia Reperfusion Injury in Male Rats — Qayssar Joudah Fadheel, Zahraa I. J. Shubber · Wiadomości Lekarskie (2025) | TGRS Research Map | TGRS