Lost to Follow-Up After Patent Foramen Ovale (PFO) Closure: Late Detection of Abdominal Aortic Embolization of an Occluder Device

Embolization of a patent foramen ovale (PFO) occluder is a rare complication, particularly when detected years after device implantation. We report a case of a 30-year-old patient who initially presented with acute right lower limb ischemia caused by embolic occlusion of multiple arteries. A floating thrombus was detected in the inferior vena cava, and subsequent evaluation revealed a PFO, a bicuspid aortic valve, and an aortic arch anomaly. Six weeks later, PFO closure was performed using a 25 mm Amplatzer Cribriform device (Abbott, Chicago, Illinois), followed by appropriate post-procedural antithrombotic therapy. Nearly five years after implantation, routine follow-up revealed asymptomatic embolization of the occluder to the suprarenal abdominal aorta at the level of the superior mesenteric artery, without evidence of limb or renal hypoperfusion; the exact timing of embolization could not be determined. Percutaneous retrieval was attempted but aborted due to pain and the high risk of aortic injury, and the device was therefore left in situ. This case highlights a rare late complication of PFO closure and underscores the importance of long-term surveillance in patients with complex cardiovascular anatomy and thrombotic risk factors.

Authors

Institutions

Publication Details

Journal
Cureus
Published
2026-01-30
DOI
https://doi.org/10.7759/cureus.102632
Primary Topic
Cardiovascular and Diving-Related Complications
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Lost to Follow-Up After Patent Foramen Ovale (PFO) Closure: Late Detection of Abdominal Aortic Embolization of an Occluder Device

Amir Hakanovic, Mirza Kovačević, Igal Moarof, Minela Hadzic Abdurahmanovic
Cureus
Cardiovascular and Diving-Related Complications
article

Lost to Follow-Up After Patent Foramen Ovale (PFO) Closure: Late Detection of Abdominal Aortic Embolization of an Occluder Device

Amir Hakanovic, Mirza Kovačević, Igal Moarof, Minela Hadzic Abdurahmanovic
article en

Abstract

Embolization of a patent foramen ovale (PFO) occluder is a rare complication, particularly when detected years after device implantation. We report a case of a 30-year-old patient who initially presented with acute right lower limb ischemia caused by embolic occlusion of multiple arteries. A floating thrombus was detected in the inferior vena cava, and subsequent evaluation revealed a PFO, a bicuspid aortic valve, and an aortic arch anomaly. Six weeks later, PFO closure was performed using a 25 mm Amplatzer Cribriform device (Abbott, Chicago, Illinois), followed by appropriate post-procedural antithrombotic therapy. Nearly five years after implantation, routine follow-up revealed asymptomatic embolization of the occluder to the suprarenal abdominal aorta at the level of the superior mesenteric artery, without evidence of limb or renal hypoperfusion; the exact timing of embolization could not be determined. Percutaneous retrieval was attempted but aborted due to pain and the high risk of aortic injury, and the device was therefore left in situ. This case highlights a rare late complication of PFO closure and underscores the importance of long-term surveillance in patients with complex cardiovascular anatomy and thrombotic risk factors.

CureusVol. 18(1)
University of Zenica (BA), Hôpital régional (CH), Kantonsspital Aarau (CH)
Good health and well-being
Openalex Percentile: Top 73%
Cardiovascular and Diving-Related Complications
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.