Adipocyte fatty acid‐binding protein as a cerebrospinal fluid–accessible biomarker and druggable target in subarachnoid haemorrhage: Linking fatty acid dysregulation to microglial neuroinflammation
A-FABP is a promising biomarker and translatable therapeutic target to improve SAH outcome. Targeting A-FABP disrupts fatty acids-driven neuroinflammation and microglial metabolic reprogramming to reduce brain injury after SAH.
Authors
- Boyang Wei (ORCID: https://orcid.org/0000-0003-1252-8200)
- Hao Tian
- Lingling Shu (ORCID: https://orcid.org/0000-0002-3956-8563)
- Xi Zhang (ORCID: https://orcid.org/0000-0002-4638-3997)
- Xin Feng (ORCID: https://orcid.org/0000-0002-4874-8048)
- Xingwu Liu (ORCID: https://orcid.org/0000-0001-8304-3126)
- Chuanzhi Duan
- Xifeng Li
- Zhiyuan Zhu
- Wenchao Liu
- Shenquan Guo
- Jingjing Kong
- Lei Jin
- Ran Li
Institutions
- Sun Yat-sen University (CN)
- Zhujiang Hospital (CN)
- Sun Yat-sen University Cancer Center (CN)
- University of Hong Kong (HK)
Publication Details
- Journal
- Clinical and Translational Medicine
- Published
- 2026-01-30
- DOI
- https://doi.org/10.1002/ctm2.70607
- Primary Topic
- Intracerebral and Subarachnoid Hemorrhage Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China